CTLA4[Biotinylated]:B7-2 Inhibitor Screening Assay Kit

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Cat.No.: Kit-1713
Product Overview: B7-2 (CD86) signaling through CTLA4(CD152) has been shown to inhibit T cell activation. This co-inhibitory pathway can be overactive in many tumors, enabling cancers to escape the host"s immune system. CTLA4-blocking antibodies, including Ipilimumab (Yervoy) and Tremelimumab, have shown clinical efficacy in treating cancer.

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