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![CTLA4:B7-1[Biotinylated] Inhibitor Screening Assay Kit](https://www.b2bgood.com/en/file/upload/201704/18/1641017741869.jpg)
CTLA4:B7-1[Biotinylated] Inhibitor Screening Assay Kit
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| Cat.No.: | Kit-1712 |
| Product Overview: | The activation of native T cells requires two signals, the specific T cell receptor recognition of MHC/Antigen on the surface of the antigen-presenting cell (APC), and the binding of B7-1 (CD80) ligand on the APC with the CD28 receptor on the T cell surface. Conversely, binding of CTLA4 to B7-1 on the T-cell surface results in an inhibitory signal and prevents T-cell activation. CTLA4:B7-1 interaction is an important drug target for the regulation of the host"s response to cancer. |
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